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6-Methoxy-2-naphthaldehyde

6-Methoxy-2-naphthaldehyde

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6-Methoxy-2-naphthaldehyde Basic information
6-Methoxy-2-naphthaldehyde
LABOTEST-BB LT01147524;ASINEX-REAG BAS 07663025;6-METHOXY-2-NAPHTHALDEHYDE;TIMTEC-BB SBB010060;6-methoxy-2-naphthalaldehyde;6-methoxynaphthalene-2-carbaldehyde;6-Methoxy-2-Naphtaldehyde;6-Methoxy-2-naphthaldehyde,99%
3453-33-6
C12H10O2
186.21
222-377-2
Building Blocks;C10-C12;Aromatic Aldehydes & Derivatives (substituted);Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Aldehydes;C10 to C21;Carbonyl Compounds;1;bc0001
3453-33-6.mol
6-Methoxy-2-naphthaldehyde Structure
 
6-Methoxy-2-naphthaldehyde Chemical Properties
81-84 degree (lit.)
196 degree / 10mmHg
1.169±0.06 g/cm3(Predicted)
0.022Pa at 25 degree
under inert gas (nitrogen or Argon) at 2-8 degree
150.1mg/L at 25 degree
1945989
2.97 at 25 degree
3453-33-6(CAS DataBase Reference)
 
36/37/38
26-36-24/25-37/39
3
29124990
 
 
6-Methoxy-2-naphthaldehyde Usage And Synthesis
yellow to beige-yellow crystals or crystalline
6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluorescent substrates for inhibition studies relating to hypertension and vascular inflammation. It is also used as intermediate of Nabumetone.
6-Methoxy-2-naphthaldehyde may be used in the preparation of the following 4-(6-methoxy-2-naphthyl)butan-2-one related compounds:

4-(6-methoxy-2-naphthyl)but-3-en-2-one

4-(6-methoxy-2-naphthyl)-3-methylbutan-2-one

5-(6-methoxy-2-naphthyl)pentan-3-one


(2E)-1-(2-hydroxyphenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

(2E)-1-(2-chloropyridin-4-yl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

(2E)-3-(6-methoxy-2-naphthyl)-1-pyridin-4-ylprop-2-en-1-one

(2E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

The Journal of Organic Chemistry, 53, p. 4587, 1988 10.1021/jo00254a035
6-Methoxy-2-naphthaldehyde can be prepared by reacting 2-bromo 6-methoxy naphthalene with triethylorthoformate via Grignard reaction. Its crystals belong to the orthorhombic space group, P212121 and shows excellent NLO (non-linear optical) property.
 
6-Methoxy-2-naphthaldehyde Preparation Products And Raw materials
Tetrahydrofuran-->Acetic acid-->N,N-Dimethylformamide-->Government regulation-->n-Butyllithium-->Tin-->2-Methoxynaphthalene
6-Methoxy-2-vinylnaphthalene-->6-Hydroxy-2-naphthaldehyde-->6-Methoxy-2-Acetyl Naphthalene-->NABUMETONE RELATED COMPOUND A (15 MG) (1-(6-METHOXY-2-NAPHTHYL)-BUT-1-EN-3-ONE)-->(6-methoxynaphthalen-2-yl)methanamine-->2,2,2-TRIFLUORO-1-(6-METHOXY-NAPHTHALEN-2-YL)-ETHANONE

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