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2,4-Dihydroxyacetophenone

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2,4-Dihydroxyacetophenone Basic information

	2,4-Dihydroxyacetophenone
	Resoacetophenone;Resorcinol, 4-acetyl-;2,4-Dihydroxyacetoph;NSC 10883;NSC 37559;4-Acetylresorcinol Resacetophenone;HyMechroMone;IMp. A (EP): 1,3-Dihydroxybenzene (Resorcinol)
	89-84-9
	C8H8O3
	152.15
	201-945-3
	Aromatics;Miscellaneous Reagents;Acetophenone Series;Aromatic Acetophenones & Derivatives (substituted);Benzene series;89-84-9;bc0001;john's
	89-84-9.mol

2,4-Dihydroxyacetophenone Chemical Properties

	143-144.5 degree (lit.)
	234.6 degree (rough estimate)
	1.18 g/mL at 25 degree (lit.)
	1.4945 (estimate)


	7.96±0.18(Predicted)

	Off-white to pink to brown
	5 (1g/l, H2O, 20 degree )

	14,8140
	1282505
	SULYEHHGGXARJS-UHFFFAOYSA-N
	1.480 (est)
	89-84-9(CAS DataBase Reference)
	Ethanone, 1-(2,4-dihydroxyphenyl)-(89-84-9)
	Ethanone, 1-(2,4-dihydroxyphenyl)- (89-84-9)

2,4-Dihydroxyacetophenone Usage And Synthesis

	2,4-Dihydroxyacetophenone appears as a yellow-brown to reddish-brown fine crystalline powder. It slowly decomposes in water and can dissolve in hot alcohol, pyridine, and glacial acetic acid. In contrast, it is nearly insoluble in ether, benzene, and chloroform. A reaction with iron chloride causes it to adopt a red hue.
	2,4-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis. It is also used as intermediate for pharmaceuticals. Reagent for iron as a 10% alcoholic solution. A red color is obtained with ferric ions in slightly acid solution: Cooper, Ind. Eng. Chem. Anal. Ed. 9, 334 (1937).
	ChEBI: 2',4'-dihydroxyacetophenone is a dihydroxyacetophenone that is acetophenone carrying hydroxy substituents at positions 2' and 4'. It has a role as a plant metabolite. It is a member of resorcinols and a dihydroxyacetophenone.
	with zinc chloride (Nencki reaction) (94%) with Amberlite IR-120 (a cation exchange resin, sulfonic acid type) (87%) with polyphosphoric acid (63%) with 70% perchloric acid (33%).
	Journal of the American Chemical Society, 70, p. 428, 1948 10.1021/ja01181a521

	2,4-Dihydroxyacetophenone is obtained by the acetylation of resorcinol and acetic acid. In addition, it can also be obtained by reacting resorcinol with chloroacetyl or acetic anhydride in the presence of zinc chloride.

2,4-Dihydroxyacetophenone Preparation Products And Raw materials


	7-Hydroxycoumarin-->1-[4-(Benzoyloxy)-2-hydroxyphenyl]-3-phenyl-1,3-propanedione-->1-(2,4-Bis(benzoyloxy)phenyl)ethanone-->7-HYDROXYFLAVONE-->2',4'-DIHYDROXYCHALCONE-->3,7-DIHYDROXYFLAVONE-->4-HYDROXY-7-METHOXYCOUMARIN-->7-HYDROXYFLAVANONE-->ROBINETIN-->4'-Benzyloxy-2'-hydroxyacetophenone-->4-Ethylresorcinol-->4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol-->2,4-Dimethoxyacetophenone

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